Dr. Tengfei Guo

tengfei.guo@pku.edu.cn

Dr. Tengfei Guo is interested in studying the early abnormal signs of AD using multi-model neuroimaging and biofluid markers (including plasma and CSF biomarkers) in cognitively unimpaired (CU) and cognitively impaired (CI) older adults as well as in AD mouse models. His lab investigates the relations of Aβ, tau, synapse loss, brain atrophy, cortical thinning, hypometabolism, and cognitive decline across different clinical and biological stages of AD. The ultimate goal is to understand the characteristics of AD pathologies, detect AD as early as possible, and provide novel insights into the early intervention of AD.

Education and Experience

10/2021-Present, Assistant Professor, Peking University Shenzhen Graduate School

12/2020 - Present, Junior PI, Shenzhen Bay Laboratory

5/2018-11/2020, Postdoctoral Fellow, University of California, Berkeley, advised by Prof. William Jagust

11/2014 - 4/2018, PhD, Technical University of Munich, Germany, advised by Prof. Markus Schwaiger and Prof. Timo Grimmer

9/2013 - 9/2014, MSc in Medical Physics, Heidelberg University, Germany

9/2011 - 9/2013, M.E. in Biomedical Engineering, Shanghai Jiao Tong University,

9/2007 - 6/2011, B.E. in Medical information Engineering, Sichuan University

Research Interests

Aging, Alzheimer’s disease, and vascular disease

PET/CT imaging (Aβ, Tau, FDG), MRI imaging (T1, T2 FlAIR, Resting fMRI, DTI, ASL and etc.)

CSF/Plasma biomarkers

Neuroscience, neurobiology

Neuromodulation

Fundings

Nature Science Foundation of China (NSFC) for Excellent Young Scholars, 2025-2027, ongoing, PI.

Guangdong Science Foundation for Distinguished Young Scholars, 2023-2026, ongoing, PI.

Shenzhen basic research Foundation for Excellent Young Scholars, 2023-2026, ongoing, PI.

Nature Science Foundation of China (NSFC) General Project, 2022 to 2025, ongoing, PI.

Shenzhen Bay Laboratory Key Cultivating Project, 2021-2022, joint PI.

Shenzhen Bay Laboratory Open project, 2020-2023, joint PI.

Awards

2023 Alzheimer's Association Internaitonal Conference “Young Investigator Travel Scholarship”

2020 American Alzheimer’s Association “Young Investigator” Honorable Mention Award

2020 Human amyloid imaging “Young Investigator Travel Scholarship”

2018 Alavi-Mandell Publication Award, Society of Nuclear Medicine & Molecular Imaging (SNMMI)

Services

Association: International Alzheimer’s Association ISTAART “PIA to Elevate Early Career Researchers (PEERs)”, Asia lead, 2021-2024

Journal Editor: Alzheimer’s & Dementia; Journal of Alzheimer disease

Contact details